The southern half of the province of Burgos is a mosaic of surprises that span centuries of history, further highlighting the cultural heritage of a territory full of singularities.

Clunia Sulpicia was one of the most important Roman cities in Hispania. It was founded in the time of Emperor Tiberius and General Sulpicius Galba proclaimed himself emperor.

The city experienced its maximum splendor between the 1st and 2nd centuries AD and good proof of this are the remains found of luxurious buildings decorated with magnificent mosaics. Walking through the archaeological site is a journey through time from the first moment with the vision of the Roman theater or the baths, which already denotes the magnitude of a city that is estimated to have had thirty thousand inhabitants.

The large forum, in which the remains of the taverns that flanked it are preserved, also gives the measure of the intense daily social activity of the metropolis.

A short distance away, the town of Caleruega, whose origin dates back to the 10th century as a fortified town structured around the Guzmanes tower and birthplace of Santo Domingo de Guzmán, displays its imposing monastery of Santo Domingo de Caleruega among a simple farmhouse. Inside, the cloister is notable, reminiscent of its first Romanesque traces. Attached to the monastic precinct, the church of Santo Domingo preserves an interesting Renaissance and two Baroque altarpieces, as well as a Gothic choir as the only exponent of the primitive church on which the current one was rebuilt.

Continuing towards the south, the silhouette of the Peñaranda de Duero castle breaks the horizon between fields of vineyards. At its feet lies a medieval town of emblazoned houses and cobblestone streets, declared a Historic Site, whose life revolves around the Plaza Mayor. One side is closed by the palace of the Counts of Miranda, displaying a magnificent Plateresque doorway, while its interior preserves a magnificent patio and beautiful halls decorated with Mudejar and Plateresque motifs.

The opposite side of the square is closed by a group of porticoed houses, testimony of the popular architecture of the area, and the collegiate church of Santa Ana, an imposing baroque temple that houses a magnificent neoclassical altarpiece by Ventura Rodríguez. On that same side of the square there is a splendid scroll of justice from the 15th century, which denotes the importance of the town in the past by having the power to administer justice.

Already in the land of wines of the Ribera del Duero Designation of Origin, next to the river the monastery of Santa María de la Vid displays its splendor. Its origins date back to the 12th century, but there are hardly any remains of its first Romanesque construction, as over time it underwent transformations until its current appearance, a consequence of the last reform carried out in the 16th century. Externally, its baroque belfry stands out among the sobriety of the complex, but it is inside where it houses true jewels such as the library, the monumental church, the twenty-three copies of incunabula, the Bestiary of Don Juan of Austria from 1570, the only one that exists in Spanish language and the medieval manuscript of Our Lady of the Vine from the 14th century.